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Government Cracks Down on 16 Fixed Dose Medicines Citing Safety Issues

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The Center has banned 16 fixed-dose combination (FDC) medicines across India, stating that these drug formulations do not have adequate therapeutic justification and that the potential risks associated with their use outweigh any proven benefits.

The Union Health Ministry said the decision was taken in the interest of public health and forms part of the government’s broader effort to encourage the rational use of medicines while ensuring that only scientifically validated treatments remain available in the market.

Fixed-dose combination drugs contain two or more active pharmaceutical ingredients combined in predetermined proportions within a single formulation.

The prohibition follows a detailed review of such medicines conducted in line with directions issued by the Supreme Court. As part of the exercise, the Drugs Technical Advisory Board (DTAB) appointed an expert committee to assess various drug combinations and identify formulations considered irrational, therapeutically unjustified or potentially unsafe.

Following the committee’s recommendations, the ministry announced that the manufacture, sale, distribution and supply of the identified 16 FDC drugs for human use would be prohibited with immediate effect nationwide.

According to the ministry, the banned formulations were found to offer limited therapeutic value and were not considered appropriate when weighed against the associated health risks.

The list includes medicines from several treatment categories, such as pain-relief drugs, antispasmodics, antibiotics and dermatological products.

Among the combinations prohibited are Acetyl Salicylic Acid with Ethoheptazine, Dicyclomine with Paracetamol and Clidinium Bromide, Dicyclomine with Paracetamol, Clidinium Bromide and Chlordiazepoxide, Gliclazide with Chromium Picolinate, and Paracetamol with Lignocaine.

Several antibiotic combinations have also been barred, including formulations containing Amoxicillin and Serratiopeptidase, Amoxicillin with Serratiopeptidase and Lactobacillus Sporogenes, Amoxicillin with Cloxacillin, Lactic Acid Bacillus and Serratiopeptidase, Cefadroxyl with Probenecid, and Cefuroxime with Serratiopeptidase.

The ban additionally covers a number of skincare and dermatological products that combine Aloe Vera or Aloe Extract with ingredients such as Vitamin E, Jojoba Oil, Orange Oil, Wheat Germ Oil, Tea Tree Oil, Allantoin and D-Panthenol.

The ministry issued the notifications under Section 26A of the Drugs and Cosmetics Act, 1940.

Officials said the latest action is part of an ongoing initiative to strengthen patient safety and eliminate irrational drug combinations from the market. The ministry noted that several similar FDC formulations have been prohibited in recent years following scientific evaluation and regulatory review.

State drug regulators and enforcement authorities across the country have been instructed to ensure strict implementation of the ban. Manufacturers, distributors, importers and other stakeholders have also been directed to take the necessary steps to comply with the new regulations.

‘No Press Freedom’: JD Vance Details What Held Up Full US-Iran Deal Publication

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jd vance
jd vance

US Vice President JD Vance has suggested that the delay in releasing the full text of the peace agreement between the United States and Iran, known as the “Islamabad Memorandum of Understanding”, may have stemmed from differences in media freedoms in the countries involved in mediating the deal.

His comments came shortly after Washington and Tehran formally signed the agreement on Wednesday, bringing an end to more than 100 days of conflict in West Asia.

Questions over the delayed publication of the agreement

Pakistan and Qatar played key roles in facilitating talks between the two sides.

Pakistan Prime Minister Shehbaz Sharif was among the first leaders to publicly announce that the United States and Iran had agreed to a ceasefire, referring to the framework as the “Islamabad Memorandum of Understanding” in a social media post earlier this week.

According to a Bloomberg report, discussions with Pakistani officials, combined with separate backchannel engagement involving Qatari representatives, helped the US administration gain a better understanding of Iran’s political landscape and advance negotiations.

The report added that Qatar’s intervention at a crucial stage helped secure the temporary agreement.

Despite the announcement, questions remained after the complete text of the 14-point memorandum was not released immediately.

Vance points to differences in press freedom

Speaking on The New York Times podcast Interesting Times with Ross Douthat, Vance said differing expectations around transparency may have contributed to the delay.

When asked what the agreement achieved that could not have been secured without months of conflict, Vance responded by stressing the importance of making the document public.

“We actually want to get the text out because it’s difficult to have a meaningful discussion without people being able to read it,” he said.

Vance added that countries involved in the mediation process do not necessarily operate under the same expectations regarding public disclosure.

“I think part of the disconnect is that in the Pakistani and Qatari systems, they don’t really have the First Amendment and freedom of the press in the same way. There isn’t always the expectation that the text will immediately be available for the public to scrutinise, analyse and debate,” he said.

The First Amendment to the US Constitution protects several fundamental freedoms, including freedom of speech, religion, the press, assembly and the right to petition the government.

Vance went on to outline key elements of the agreement, noting that it would lead to the reopening of the Strait of Hormuz and that Iranian forces had ceased military operations the previous day, describing the development as a significant step forward.

What the agreement includes

The interim understanding between Washington and Tehran is designed to halt hostilities, restore navigation through the Strait of Hormuz and restart negotiations over Iran’s nuclear programme.

The arrangement also allows Iran to resume unrestricted oil exports, providing an immediate economic benefit to Tehran.

Beyond that, analysts note that both countries have effectively returned to a position similar to where they stood before the conflict escalated following military action by Israel and the United States earlier this year.

The next phase of diplomacy is expected to begin on Saturday, when US envoy Steve Witkoff and Iranian Foreign Minister Abbas Araghchi meet in Switzerland for a 60-day round of negotiations aimed at reaching a broader agreement.

Supreme Court of India Says Right to Walk on Designated Footpaths Is a Fundamental Right

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SUPREME COURT
SUPREME COURT

In a landmark ruling, the Supreme Court on Thursday declared that the right to walk on a designated footpath is a fundamental right, holding that pedestrians must be given priority over motorized vehicles on demarcated walkways.

The judgment, delivered by a bench of Justices PS Narasimha and AS Chandurkar, stated that the right to walk is an essential component of the freedom of movement guaranteed under Article 19(1)(d) of the Constitution and is closely linked to other fundamental rights, including the right to life and personal liberty under Article 21.

The court observed that citizens have a primary right to use footpaths and that this right must take precedence over vehicular movement wherever pedestrian infrastructure exists.

“The right to walk is a fundamental right under Part III of the Constitution. It is integral to the freedom of movement and extends to the right to safe and demarcated footpaths. These rights are primary and shall have priority over motorized transport,” the bench held.

The ruling came while hearing a motor accident compensation case involving a father who lost his five-year-old son in a road accident while taking him to school.

Highlighting the responsibilities of public authorities, the court said the right to walk carries a corresponding obligation on governments and civic bodies to create and maintain pedestrian infrastructure.

“If a road exists, there is a duty to ensure the presence of clearly demarcated and properly maintained footpaths,” the bench said.

It identified urban development authorities, municipal corporations, municipalities and panchayats as the agencies responsible for constructing, preserving and safeguarding footpaths and pedestrian facilities.

The court further held that citizens whose right to walk is violated can seek constitutional and legal remedies, including compensation and restitution. It clarified that such remedies would be separate from those available under the Motor Vehicles Act.

The bench directed the Supreme Court registry to forward the judgment to the relevant central ministries and the Law Commission for consideration of an appropriate legal framework.

Emphasising the historical importance of pedestrian rights, the court remarked that people were walking long before the invention of wheeled transport and that the freedom to walk is the most basic form of movement protected by the Constitution.

“The fundamental right to walk predates the right to move on wheels. Citizens must be guaranteed safe, accessible and well-defined footpaths,” the court observed.

The judges lamented that pedestrian rights have long been overlooked, noting that rapid growth in motorised transport has pushed walkers to the margins and often turned footpaths into spaces dominated by vehicles.

“It is unfortunate that pedestrians are frequently treated as obstacles while roads and footpaths are increasingly taken over by motor vehicles. This situation must change,” the court said.

The bench also criticised the Motor Vehicles Act for being primarily vehicle-centric, arguing that pedestrian interests have traditionally been treated as secondary concerns.

According to the court, the lack of safe and accessible footpaths has evolved into a broader societal issue. It stressed that the right to walk requires nothing more than secure and comfortable spaces where citizens can move freely without fear.

Reaffirming its position, the court said that whenever a road is built, authorities must ensure the provision and upkeep of footpaths. It added that this obligation is enforceable and that pedestrian rights will override the privileges enjoyed by motor vehicles on designated walkways.

In the case before it, the Supreme Court restored and enhanced the compensation awarded to the child’s father, directing payment of ₹11.44 lakh within two months and setting aside a High Court order that had reduced the amount.

The court also ordered the registration of a separate matter titled “Re: Fundamental Right to Walk and Footpath”, impleading the Union government through the Ministries of Housing and Urban Affairs, Rural Development, and Road Transport and Highways. Additional Solicitor General KM Nataraj has been asked to assist the court in the proceedings.

Jio IPO Process Moves Ahead with SEBI Submission Planned for Today

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reliance jio
reliance jio

Reliance Industries Chairman and Managing Director Mukesh Ambani on Friday announced that the board of Jio Platforms has approved plans for an Initial Public Offering (IPO), with the company set to file its Draft Red Herring Prospectus (DRHP) with the Securities and Exchange Board of India (SEBI) later in the day.

Speaking at Reliance Industries’ 49th Annual General Meeting, Ambani said the listing process will be spearheaded by Isha Ambani, Akash Ambani and Anant Ambani.

“The Reliance Board has approved the Jio IPO. The Draft Red Herring Prospectus will be filed today. Isha Ambani, Akash Ambani, and Anant Ambani will lead the project,” he said.

The proposed public issue marks the first major listing from the Reliance group in nearly two decades. Highlighting the significance of the move, Ambani said a public listing would showcase India’s ability to create technology companies with global scale and influence.

“Listing Jio will demonstrate to the world that India can build technology companies of global scale, capability and value. I assure shareholders and future investors that Jio’s best days are still ahead,” he added.

An IPO, or Initial Public Offering, allows a company to offer its shares to the public for the first time and become a publicly traded entity. Companies typically pursue IPOs to raise capital and broaden their investor base.

According to a Bloomberg report, Jio Platforms’ board has approved the issuance of up to 270 million new shares with a face value of ₹10 each as part of the offering.

Reports earlier this year indicated that Jio was finalising its Draft Red Herring Prospectus and preparing to submit the required documents to SEBI.

Momentum around the listing gained after the government revised listing norms for large companies. Under the updated rules, firms with a post-issue valuation exceeding ₹5 trillion, or roughly $54 billion, can now list by diluting a minimum of 2.5% of their equity. This is lower than the earlier 5% requirement for mega-cap companies and significantly below the standard 25% public shareholding norm.

The regulatory change is widely seen as one of the key factors that accelerated plans for Jio Platforms’ much-anticipated stock market debut.

OpenAI Scores Key Hiring Victory as Top Google Researcher Switches Sides

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chatgpt
chatgpt

One of Google’s most influential AI researchers is set to join OpenAI, marking a significant setback for Alphabet in the intensifying race to build the world’s most advanced artificial intelligence systems.

Noam Shazeer, widely regarded as one of the key figures behind the modern AI revolution, announced his departure in a post on X. His move represents a major boost for OpenAI as it continues competing with rivals such as Anthropic to develop increasingly powerful AI models ahead of a potential public listing.

OpenAI Chief Research Officer Mark Chen confirmed that Shazeer will lead the company’s AI architecture research efforts, focusing on the design and development of future AI models. Shazeer said he is excited to join OpenAI and work alongside what he described as an exceptional team.

His exit comes at a crucial time for Google, which remains locked in fierce competition with OpenAI, Anthropic, and other major players in the rapidly evolving AI sector.

Although Google has benefited from growing investor enthusiasm around its AI initiatives, including its Gemini models, custom chips, and consumer products, the company has faced criticism for lagging behind in certain areas, such as AI coding tools for businesses. Former employees have also pointed to internal hurdles that researchers face when trying to access computing resources.

Shazeer is best known for co-authoring the landmark 2017 research paper Attention Is All You Need, which introduced the transformer architecture that powers today’s generative AI systems. During his first stint at Google, which began in 2000, he contributed to several major products, including the company’s spelling correction technology and advertising systems.

In 2021, he left Google to launch Character.AI after becoming frustrated with the company’s pace in bringing generative AI products to market. He returned to Google in 2024 through a licensing agreement that valued Character.AI at approximately $2.5 billion and later helped lead the development of Google’s flagship Gemini AI model.

Responding to the news, a Google spokesperson thanked Shazeer for his contributions over the years and wished him success in his future endeavors.

Poll Reveals Barack Obama Holds Strongest Public Support Among Former and Current Presidents

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Barack Obama
Barack Obama

Former US President Barack Obama remains the most popular living former president in the United States, according to a new CNN poll, comfortably ahead of both President Donald Trump and former President Joe Biden.

The survey, conducted by SSRS for CNN among 2,480 adults across the country, found that 57% of respondents view Obama favorably. Trump received a favorability rating of 34%, while Biden trailed at 30%.

The findings come as Obama prepares to open his long-awaited presidential center.

Obama leads among independent voters

The poll suggests Obama’s popularity extends beyond the Democratic Party. Among independent voters, his favorability rating is more than double that of either Trump or Biden. He also continues to command overwhelming support among Democrats.

While only around 20% of Republicans said they view Obama favorably, CNN noted that he still attracts more support from across party lines than either Trump or Biden.

Bush and Clinton’s ratings

The survey also gauged public opinion of other living former presidents.

Former President George W. Bush registered a 42% favorable rating against 33% unfavorable, giving him a slightly positive overall standing.

Bill Clinton, meanwhile, remains a more divisive figure, with Americans almost evenly split between favorable and unfavorable views.

CNN noted that former presidents often see their public image improve after leaving office. Bush’s reputation has rebounded considerably since departing the White House with low approval ratings.

Trump also experienced a rise in favorability before beginning his second term, reaching 46%, though those numbers have since declined.

Biden, on the other hand, currently holds the lowest favorability rating of his post-presidency. While negative views of him have softened somewhat, more Americans now say they have no opinion of the former president.

Most admired US president

When respondents were asked which US president they admire the most, Obama finished at the top with support from 30% of participants.

Trump ranked second with 19%, followed by Abraham Lincoln and Ronald Reagan at 9% each. John F. Kennedy received 6%, while George Washington secured 5%.

Among living presidents, Bill Clinton was named by 2% of respondents, while Biden and George W. Bush were each selected by 1%.

Nearly one in ten respondents said they did not admire any US president or chose not to answer.

Among Democratic voters, 64% named Obama as the president they admire most. Kennedy, Lincoln and Franklin D. Roosevelt followed well behind. Among Republicans, Trump led comfortably with 53% support, ahead of Reagan at 18%, Lincoln at 8%, and Kennedy and Washington at 5% each.

The poll was conducted between May 7 and May 31 through a mix of online and telephone interviews involving 2,480 adults across the United States.

No CBFC Cuts Yet for Spider-Man: Brand New Day, Sony Pictures Dismisses Runtime Speculation as ‘Inaccurate’

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spider man: brand new day
spider man: brand new day

Sony Pictures Entertainment India has dismissed speculation that Spider-Man: Brand New Day starring Tom Holland and Zendaya was censored by the Central Board of Film Certification (CBFC). The studio clarified that the film has not yet been submitted for certification in India, making reports of runtime cuts or censorship entirely unfounded.

How the speculation began

The rumours surfaced after fans spotted differing runtimes across cinema listings. While international chains such as Cineworld listed the film with a runtime of 2 hours and 30 minutes, a temporary listing on PVR Cinemas showed a runtime of 2 hours and 25 minutes.

The discrepancy quickly fueled online speculation, with some assuming the CBFC had already ordered cuts for the Indian release. Sony Pictures Entertainment India has now clarified that no certification process has taken place so far.

In an official statement, the studio said: “We love the excitement around Spider-Man: Brand New Day. To address speculation circulating online, the film has not yet been submitted to the CBFC in India, and any reports regarding certification are inaccurate. For verified information, please follow our official channels.”

Advance bookings now underway

At the same time, Sony Pictures Entertainment India has opened advance bookings for audiences across the country.

Shony Panjikaran, General Manager and Head of Sony Pictures Releasing International India, said the studio aims to make Spider-Man’s return to cinemas a major theatrical event.

“Spider-Man has a special connection with Indian audiences, and every new film becomes a celebration across generations. With Spider-Man: Brand New Day, we wanted to deliver the most immersive theatrical experience possible while allowing fans to secure their tickets early and enjoy the film across premium large-format screens,” he said.

About the film

Directed by Destin Daniel Cretton, Spider-Man: Brand New Day has been written by Chris McKenna, Erik Sommers and Justin Kuritzkes. The film is based on the Marvel character created by Stan Lee and Steve Ditko.

The production team includes Kevin Feige, Amy Pascal, Avi Arad and Rachel O’Connor, while Louis D’Esposito and David Cain serve as executive producers.

Alongside Holland and Zendaya, the cast features Sadie Sink, Jacob Batalon, Jon Bernthal, Tramell Tillman, Michael Mando and Mark Ruffalo.

The story follows Peter Parker as he embraces life as Spider-Man in a world that no longer remembers him. As his former friends move on and a mysterious new threat emerges, Peter finds himself facing challenges that could reshape his future.

Spider-Man: Brand New Day is scheduled to release in India on July 30, 2026, one day before its debut in several international markets. The film will be available in English, Hindi, Tamil, Telugu, Kannada and Malayalam.

Audiences will also be able to experience the film in several premium formats, including P[XL], Big Pix, ScreenX, ICE, 4DX and MX4D.

Centre’s Temporary Block on Telegram Faces Legal Challenge Ahead of NEET Re-Test

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telegram
telegram

Messaging platform Telegram on Wednesday moved the Delhi High Court, challenging the temporary restrictions imposed on the app ahead of the NEET UG re-examination scheduled for June 21.

The Center had ordered a temporary suspension of Telegram services in India until June 22, a move welcomed by the National Testing Agency (NTA), which said the restrictions were aimed at curbing fraud and misinformation targeting exam aspirants.

The matter has been listed before Justice Tajas Karia and is expected to be heard later in the day.

The legal challenge comes after the NTA claimed to have uncovered a large network of scammers operating through Telegram channels. According to the agency, fraudsters were allegedly charging students amounts ranging from ₹14,000 to ₹25,000 and, in some cases, as much as ₹10 lakh by falsely promising access to leaked NEET re-examination papers.

Details of the restriction order

In a statement, the NTA said the Ministry of Electronics and Information Technology (MeitY) had directed temporary restrictions on Telegram across India until June 22, covering both the examination period and the days immediately following it.

The ministry also instructed the platform to disable its message-editing feature in India until June 30.

According to the NTA, the measures were introduced to disrupt organized cheating networks that were allegedly using Telegram to spread false claims about access to examination papers. The agency added that disabling message editing would help prevent the creation of fake paper leak evidence, where users could alter older messages while retaining their original timestamps.

While acknowledging that the restrictions would inconvenience legitimate Telegram users, the NTA maintained that the measures were temporary and necessary to safeguard the integrity of NEET UG. The examination, originally conducted on May 3, was later canceled amid allegations of paper leaks and other irregularities.

Pavel Durov criticizes the decision

Meanwhile, Telegram founder Pavel Durov criticized the temporary ban, arguing that it unfairly affected millions of ordinary users.

“India’s IT ministry banned Telegram for one week because some users shared leaked exam questions. This punishes more than 150 million regular Telegram users in India, not the individuals responsible for leaking exam material. The ban also has not stopped the leaks, which have simply shifted to other platforms,” Durov said in a post on X.

NTA Director General Abhishek Singh defended the government’s action, stating that the restrictions would prevent students from accessing fraudulent channels.

He noted that while some operators might continue running channels through VPNs or from outside India, students within the country would no longer be able to access them easily.

“Some channels may continue operating from outside India or through VPNs, but if students cannot reach them, the fraud ecosystem loses its audience. This helps protect candidates from losing money and wasting time on fake question papers,” Singh said.

India Welcomes Back The Chainsmokers with New Tour Announcement

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chainsmokers
chainsmokers

Global electronic music duo The Chainsmokers, best known for hits such as Closer and Don’t Let Me Down, are set to return to India later this year with a three-city tour.

The Grammy-winning pair, comprising Drew Taggart and Alex Pall, will perform in Mumbai on December 18, Delhi on December 19, and Bengaluru on December 20, organisers announced on Wednesday.

The tour will also see The Chainsmokers headline the Mumbai leg of Sunburn Festival 2026 at Mahalaxmi Racecourse, marking the festival’s first edition at the iconic venue.

Known for a string of global hits including Paris and Something Just Like This, the duo last performed in India in 2023.

Karan Singh, CEO of Sunburn, said The Chainsmokers’ music has played a defining role in the lives of young listeners over the last decade.

“For Indian millennials and Gen Z audiences, their music has been part of some of the most memorable moments of youth culture. The excitement around seeing them perform live again reflects how nostalgia and shared experiences continue to bring fan communities together across the world.

“Our goal is to create large-scale cultural experiences where music, fandom, production and community come together in a way that matches what young India expects from live entertainment today,” Singh said in a statement.

The announcement is also a significant milestone for Sunburn as one of India’s biggest electronic music festivals expands to a new venue in Mumbai.

Formed in 2012, The Chainsmokers rose to international fame through a series of crossover dance-pop successes. Their catalogue has sold more than 118 million records globally and includes three Diamond-certified singles: Closer, Something Just Like This and the Grammy-winning Don’t Let Me Down.

The duo released the EP No Hard Feelings in 2024, followed by Breathe in 2025. Earlier this year, they also unveiled Love is Kind, a collaborative project with singer-songwriter Oaks.

Beyond music, Taggart and Pall have expanded into the technology sector through Mantis Venture Capital, the early-stage investment firm they co-founded in 2020.

US Drops ‘Indo’ from Indo Pacific Command, Reverts to USPACOM Citing Historical Legacy

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indo pacific us

The United States has officially restored the designation of the US Pacific Command (USPACOM), replacing the US Indo-Pacific Command (USINDOPACOM), the Department of War announced on Tuesday.

The decision marks a return to the command’s original identity. Created on January 1, 1947, under former US President Harry S. Truman, the command operated as USPACOM for more than 70 years and became both the oldest and largest of America’s unified combatant commands.

Announcing the change, the department said bringing back the historic name reflects the command’s long-standing legacy and contributions across the region.

“Restoring the USPACOM designation recognises the command’s rich history and reinforces a shared sense of pride among those serving in the Pacific,” the Department of War said.

Mission and responsibilities remain the same

Despite the name change, the command’s operational role will remain unchanged.

The department said USPACOM’s area of responsibility will continue to stretch from the western coast of the United States to India’s western frontier. Officials emphasised that the command’s strategic priorities and core objectives will remain intact.

“The command’s mission and its commitment to maintaining a free and open region alongside allies and partners remain unchanged,” the statement noted.

The department also highlighted the command’s extensive military history, including its involvement in shaping the post-World War II security framework in Asia, coordinating joint operations during the Korean War and the Vietnam War, and supporting numerous humanitarian and disaster relief missions over the years.

Officials added that the USPACOM name represents decades of military tradition and enduring partnerships throughout the region.

Position within the US military structure

The Department of War said its primary role is to provide military capabilities necessary for national defence and deterrence. The department oversees 11 combatant commands, each responsible for either a geographic region or a specialised mission and tasked with directing military operations during both peacetime and conflict.

USPACOM works closely with partner nations to enhance regional security, support development, deter potential threats and deliver humanitarian assistance across its area of responsibility.

The command is currently headed by Samuel Paparo. The command’s Inspector General serves as an independent adviser to the commander, conducting inspections, investigations and assistance programs aimed at improving readiness, operational effectiveness and overall mission performance.